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hepatic encephalopathy

Disease Summary
Associated Targets (18)
Tclin

8

Tchem

7

Tbio

3


GARD Rare
Mondo Description Hepatic encephalopathy is a syndrome observed in some patients with cirrhosis. It is defined as a spectrum of neuropsychiatric abnormalities in patients with liver dysfunction, when other known brain disease has been excluded.Signs and symptomsmay be debilitating, and they can begin mildly and gradually, or occur suddenly and severely. They may includepersonality or moodchanges, intellectual impairment, abnormal movements,a depressed level of consciousness, and other symptoms.There are several theories regarding the exact cause, butdevelopment of the condition isprobablyat least partiallydue to the effect of substances that are toxic to nerve tissue (neurotoxic), which are typically present with liver damage and/or liver disease. Treatment depends upon the severity of mental status changes and upon the certainty of the diagnosis.
Disease Ontology Description A brain disease that is characterized by loss of brain function, the occurrence of confusion, altered level of consciousness, and coma that results when the liver is unable to remove toxins from the blood.
Mondo Term and Equivalent IDs
MONDO:0001711:  hepatic encephalopathy
COHD:4029488: 
GARD:0010452: 
ICD9:572.2: 
MESH:D006501: 
NCIT:C79596: 
SCTID:13920009: 
UMLS:C0019151: