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granulomatosis with polyangiitis

Disease Summary
Associated Targets (9)
Tbio

5

Tclin

2

Tchem

2


Disease Ontology Description An autoimmune hypersensitivity disease that is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera, and is located_in lung, located_in kidney, located_in skin resulting from an autoimmune attack by antineutrophil cytoplasmic antibodies against small and medium-size blood vessels.
DataSource References
JensenLab Experiment TIGA:  DOID:12132
DrugCentral Indication:  DOID:12132
JensenLab Knowledge MedlinePlus:  DOID:12132
CTD:  DOID:12132
eRAM:  DOID:12132
DisGeNET:  UMLS:C3495801
GWAS Targets (27)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
1
1
0
4.2
84.2
Tbio
1
1
0
4.2
84.2
Tbio
1
1
0
4.2
84.2
Tbio
1
1
0
4.2
84.2
Tbio
1
1
0
4.2
84.2
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
4.2
84.2
Tbio
0
4.2
84.2
Tbio
0
4.2
84.2
Tbio
0
4.2
84.2
Tbio
0
4.2
84.2
Target Novelty (Tin-x)