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familial sick sinus syndrome

Disease Summary
Associated Targets (2)
Tclin

2


Explore Associated Targets
Mondo Description Sick sinus syndrome is a rare cardiac rhythm disease, usually of the elderly, characterized by electrocardiographic findings of sinus bradycardia, atrial fibrillation, atrial tachycardia sinus arrest, or sino-atrial block, and that manifest with symptoms like syncope, dizziness, palpitations, fatigue, or even heart failure. It results from malfunction of the cardiac conduction system, probably secondary to degenerative fibrosis of nodal tissue in the elderly or secondary to cardiac disorders in younger patients.
Mondo Term and Equivalent IDs
MONDO:0012061:  familial sick sinus syndrome
MESH:C563907: 
OMIMPS:608567: 
Orphanet:166282: 
SCTID:233913007: 
GWAS Targets (11)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
1
1
0
1.6
59.5
Tbio
1
1
0
1.6
59.5
Tbio
1
1
0
1.6
59.5
Tbio
1
1
0
1.6
59.5
Tbio
1
1
0
1.6
59.5
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
1.6
59.5
Tbio
0
1.6
59.5
Tbio
0
1.6
59.5
Tbio
0
1.6
59.5
Tbio
0
1.6
59.5
Target Novelty (Tin-x)
No novelty measurements found