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esophageal adenocarcinoma

Disease Summary
Associated Targets (796)
Tbio

586

Tchem

131

Tdark

42

Tclin

37


Explore Associated Targets
Mondo Description A malignant tumor with glandular differentiation arising predominantly from Barrett mucosa in the lower third of the esophagus. Rare examples of esophageal adenocarcinoma deriving from ectopic gastric mucosa in the upper esophagus have also been reported. Grossly, esophageal adenocarcinomas are similar to esophageal squamous cell carcinomas. Microscopically, adenocarcinomas arising in the setting of Barrett esophagus are typically papillary and/or tubular. The prognosis is poor.
Disease Ontology Description An esophageal carcinoma that derives_from epithelial cells of glandular origin.
Mondo Term and Equivalent IDs
MONDO:0005028:  esophageal adenocarcinoma
EFO:0000478: 
NCIT:C4025: 
ONCOTREE:ESCA: 
Orphanet:99976: 
SCTID:276803003: 
UMLS:C0279628: 
GWAS Targets (156)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
2
2
0
1.1
53.1
Tbio
2
2
0
1.1
53.1
Tbio
2
2
0
1.1
53.1
Tbio
2
2
0
1.1
53.1
Tdark
2
2
0
1.1
53.1
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
1.1
53.1
Tbio
0
1.1
53.1
Tbio
0
1.1
53.1
Tbio
0
1.1
53.1
Tdark
0
1.1
53.1
Target Novelty (Tin-x)