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demyelinating disease

Disease Summary
Associated Targets (285)
Tbio

148

Tclin

75

Tchem

45

Tdark

17


Mondo Description A broad group of disorders that affect the myelin sheaths that cover the neurons. Myelin sheathes cover neuronal axons in the central and peripheral nervous system and function to increase travelling impulse speeds. Disruption of this sheath impairs neuronal transmission and can result in disorders such as multiple sclerosis and Guillain-Barre syndrome, among others.
Mondo Term and Equivalent IDs
MONDO:0002562:  demyelinating disease
ICD10:G35.G37: 
MESH:D003711: 
NCIT:C34527: 
UMLS:C0011303: