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coronary artery disease

Disease Summary
Associated Targets (280)
Tbio

154

Tchem

84

Tclin

40

Tdark

2


Explore Associated Targets
Mondo Description Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC)
Disease Ontology Description An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles.
Mondo Term and Equivalent IDs
MONDO:0005010:  coronary artery disease
COHD:317576: 
EFO:0001645: 
GARD:0011944: 
MESH:D003324: 
NCIT:C26732: 
SCTID:414024009: 
UMLS:C1956346: 
GWAS Targets (1402)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
16
11
5
1.2
99.8
Tbio
10
12
11
1.4
99.6
Tbio
14
6
4
1.1
99
Tbio
7
7
4
1.2
98.6
Tbio
7
7
4
1.2
98.6
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
5
1.2
99.8
Tbio
11
1.4
99.6
Tbio
4
1.1
99
Tbio
4
1.2
98.6
Tbio
4
1.2
98.6
Disease Hierarchy
Target Novelty (Tin-x)