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carcinoma

Disease Summary
Associated Targets (11057)
Tbio

7476

Tdark

1680

Tchem

1414

Tclin

487


Mondo Description A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas.
Disease Ontology Description A cell type cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells.
Mondo Term and Equivalent IDs
MONDO:0004993:  carcinoma
EFO:0000313: 
MESH:D002277: 
NCIT:C2916: 
SCTID:722688002: 
UMLS:C0007097: 
Disease Hierarchy
Parents
Tbio

10537

Tdark

3071

Tchem

1769

Tclin

627

Tbio

7597

Tdark

1716

Tchem

1428

Tclin

497

Children
Tbio

5478

Tchem

1127

Tdark

1001

Tclin

374

Tbio

4961

Tchem

976

Tdark

934

Tclin

310

Tbio

4117

Tchem

858

Tdark

753

Tclin

316

Tbio

3020

Tchem

635

Tdark

464

Tclin

235

Tbio

2110

Tchem

424

Tdark

293

Tclin

146

Tbio

1272

Tchem

264

Tdark

163

Tclin

93

Tbio

1053

Tchem

283

Tdark

197

Tclin

89

Tbio

962

Tchem

217

Tdark

182

Tclin

66

Tbio

846

Tdark

182

Tchem

171

Tclin

55

Tbio

548

Tchem

152

Tdark

89

Tclin

55

Tbio

413

Tchem

88

Tdark

82

Tclin

32

Tbio

315

Tchem

55

Tdark

39

Tclin

18

Tbio

280

Tchem

52

Tdark

33

Tclin

18

Tbio

255

Tchem

53

Tclin

40

Tdark

27

Tbio

157

Tchem

83

Tclin

33

Tdark

6

Tbio

147

Tchem

61

Tdark

29

Tclin

23

Tbio

93

Tchem

55

Tclin

20

Tdark

1

Tbio

93

Tchem

42

Tclin

27

Tdark

6

Tbio

79

Tchem

32

Tclin

20

Tdark

10

Tbio

69

Tclin

30

Tchem

25

Tdark

6

Tbio

51

Tchem

35

Tclin

27

Tdark

2

Tbio

49

Tchem

24

Tclin

20

Tdark

4

Tbio

39

Tchem

20

Tdark

10

Tclin

8

Tbio

34

Tchem

17

Tclin

4

Tdark

3

Tchem

18

Tbio

11

Tclin

6

Tdark

1

Tbio

21

Tdark

6

Tchem

5

Tclin

2

Tbio

4

Tchem

3

Tclin

1

Target Novelty (Tin-x)
Too many associated targets