Pharos: autoimmune hepatitis (18 associated targets)

Disease Summary

Associated Targets (18)

Tbio

11

Tchem

4

Tclin

3

Explore Associated Targets

Mondo Description

Hepatitis caused by autoantibodies. Drugs, infections, and toxins may trigger the production of the autoantibodies against the liver parenchyma.

Disease Ontology Description

An autoimmune disease of gastrointestinal tract that results_in inflammation located_in liver caused by the body's immune system attacking the liver cells.

Mondo Term and Equivalent IDs

MONDO:0016264: autoimmune hepatitis

COHD:200762:

DOID:2048: autoimmune hepatitis

EFO:0005676:

GARD:0005871:

ICD10:K75.4:

ICD9:571.42:

MESH:D019693:

NCIT:C27029:

Orphanet:2137:

SCTID:408335007:

UMLS:C0241910:

UMLS:C1332355:

GWAS Targets (327)

Items per page:

1 – 5 of 327

Target	TDL	Study Count	SNP Count	Beta Count	Odds Ratio	Evidence (Mean Rank Score)
HLA class II histocompatibility antigen, DRB1-11 beta chain (HLA-DRB1)	Tbio	2	2	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-1 beta chain (HLA-DRB1)	Tbio	2	2	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-9 beta chain (HLA-DRB1)	Tbio	2	2	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-16 beta chain (HLA-DRB1)	Tbio	2	2	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-13 beta chain (HLA-DRB1)	Tbio	2	2	0	2.7	94.5

Items per page:

1 – 5 of 327

Target	TDL	Beta Count	Odds Ratio	Evidence (Mean Rank Score)
HLA class II histocompatibility antigen, DRB1-11 beta chain (HLA-DRB1)	Tbio	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-1 beta chain (HLA-DRB1)	Tbio	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-9 beta chain (HLA-DRB1)	Tbio	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-16 beta chain (HLA-DRB1)	Tbio	0	2.7	94.5

HLA class II histocompatibility antigen, DRB1-13 beta chain (HLA-DRB1)	Tbio	0	2.7	94.5