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autoimmune disease

Disease Summary
Associated Targets (5703)
Tbio

3907

Tchem

786

Tdark

704

Tclin

306


Explore Associated Targets
Mondo Description A disorder resulting from loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to their own tissue constituents. It may be systemic (e.g., systemic lupus erythematosus), or organ specific, (e.g., thyroiditis).
Disease Ontology Description An immune system disease that is an overactive immune response of the body against substances and tissues normally present in the body resulting from an abnormal functioning of the immune system that results in the production of antibodies or T cell directed against the host tissues.
Mondo Term and Equivalent IDs
MONDO:0007179:  autoimmune disease
COHD:434621: 
EFO:0005140: 
MESH:D001327: 
NCIT:C2889: 
OBI:1110054: 
SCTID:85828009: 
UMLS:C0004364: 
GWAS Targets (3)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tdark
1
1
0
10.7
24.5
Tdark
1
1
0
10.7
24.5
Tdark
1
1
0
10.7
24.5
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tdark
0
10.7
24.5
Tdark
0
10.7
24.5
Tdark
0
10.7
24.5
Disease Hierarchy
Parents
Tbio

4412

Tchem

872

Tdark

862

Tclin

350

Children
Tbio

2492

Tchem

471

Tdark

416

Tclin

158

Tbio

1172

Tdark

224

Tchem

214

Tclin

101

Tbio

1082

Tchem

233

Tdark

144

Tclin

98

Tbio

638

Tchem

112

Tdark

111

Tclin

100

Tbio

584

Tdark

110

Tchem

107

Tclin

97

Tchem

6

Tbio

3

Tclin

1

Tdark

1

Tchem

5

Tbio

3

Tclin

1

Tdark

1

Target Novelty (Tin-x)
Too many associated targets