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atopic dermatitis 2

Disease Summary
Associated Targets (1)


Mondo Description Any atopic eczema in which the cause of the disease is a mutation in the FLG gene.
Uniprot Description Atopic dermatitis is a complex, inflammatory disease with multiple alleles at several loci thought to be involved in the pathogenesis. It commonly begins in infancy or early childhood and is characterized by a chronic relapsing form of skin inflammation, a disturbance of epidermal barrier function that culminates in dry skin, and IgE-mediated sensitization to food and environmental allergens. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee.
Mondo Term and Equivalent IDs
MONDO:0011596:  atopic dermatitis 2