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Sjogren syndrome

Disease Summary
Associated Targets (1737)
Tbio

1219

Tchem

218

Tdark

201

Tclin

99


Explore Associated Targets
Mondo Description An autoimmune disorder in which immune cells attack and destroy the glands that produce tears and saliva. Sjögren syndrome is also associated with rheumatic disorders such as rheumatoid arthritis or systemic lupus erythematosus. The hallmark symptoms of Sjögren syndrome are dry mouth and dry eyes. In addition, Sjogren syndrome may cause skin, nose, and vaginal dryness. It also may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain
Disease Ontology Description An autoimmune hypersensitivity disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Mondo Term and Equivalent IDs
MONDO:0010030:  Sjogren syndrome
EFO:0000699: 
GARD:0010252: 
ICD9:710.2: 
MESH:D012859: 
NCIT:C26883: 
Orphanet:289390: 
SCTID:83901003: 
GWAS Targets (1680)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
4
4
0
2.3
99.2
Tbio
4
4
0
2.3
99.1
Tbio
4
4
0
2.3
99.1
Tbio
4
4
0
2.3
99.1
Tbio
4
4
0
2.3
99.1
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
2.3
99.2
Tbio
0
2.3
99.1
Tbio
0
2.3
99.1
Tbio
0
2.3
99.1
Tbio
0
2.3
99.1
Target Novelty (Tin-x)