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Psoriatic arthritis

Disease Summary
Associated Targets (199)
Tbio

155

Tchem

18

Tclin

13

Tdark

13


Uniprot Description An inflammatory, seronegative arthritis associated with psoriasis. It is a heterogeneous disorder ranging from a mild, non-destructive disease to a severe, progressive, erosive arthropathy. Five types of psoriatic arthritis have been defined: asymmetrical oligoarthritis characterized by primary involvement of the small joints of the fingers or toes; asymmetrical arthritis which involves the joints of the extremities; symmetrical polyarthritis characterized by a rheumatoid like pattern that can involve hands, wrists, ankles, and feet; arthritis mutilans, which is a rare but deforming and destructive condition; arthritis of the sacroiliac joints and spine (psoriatic spondylitis).
Disease Ontology Description A syndrome that occurs in humans with psoriasis who also experience symptoms similar to arthritis.
DataSource References
JensenLab Experiment TIGA:  DOID:9008
Monarch:  DOID:9008
JensenLab Knowledge MedlinePlus:  DOID:9008
DrugCentral Indication:  DOID:9008
CTD:  DOID:9008
eRAM:  DOID:9008
UniProt Disease:  MIM:607507
GWAS Targets (2674)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
2
4
0
11.3
97.5
Tbio
2
4
0
11.3
97.5
Tbio
2
4
0
11.3
97.5
Tbio
2
4
0
11.3
97.5
Tbio
2
4
0
11.3
97.5
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
11.3
97.5
Tbio
0
11.3
97.5
Tbio
0
11.3
97.5
Tbio
0
11.3
97.5
Tbio
0
11.3
97.5
Disease Hierarchy
Parents
Tbio

890

Tchem

179

Tdark

122

Tclin

99

Children
Target Novelty (Tin-x)