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Obesity

Disease Summary
Associated Targets (291)
Tbio

161

Tchem

85

Tclin

39

Tdark

6


Uniprot Description A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
Disease Ontology Description An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
DataSource References
JensenLab Experiment TIGA:  DOID:9970
JensenLab Knowledge UniProtKB-KW:  DOID:9970
CTD:  DOID:9970
JensenLab Text Mining:  DOID:9970
Monarch:  DOID:9970
DrugCentral Indication:  DOID:9970
Expression Atlas:  DOID:9970
UniProt Disease:  MIM:601665
Monarch:  OMIM:601665
DisGeNET:  UMLS:C0028754
GWAS Targets (36)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tchem
6
4
1
1.4
93.3
Tbio
6
4
1
1.4
93.3
Tbio
1
1
0
1.4
67.9
Tbio
1
1
0
1.4
67.9
Tbio
1
2
0
1.3
57.1
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tchem
1
1.4
93.3
Tbio
1
1.4
93.3
Tbio
0
1.4
67.9
Tbio
0
1.4
67.9
Tbio
0
1.3
57.1
Target Novelty (Tin-x)