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IgG4-related dacryoadenitis and sialadenitis
Disease Summary
Associated Targets ()
Mondo Description IgG4-related dacryoadenitis and sialoadenitis (Mikulicz disease) is an IgG4-related sclerosing disease characterized by persistent, usually painless, bilateral enlargement of the lacrimal, parotid, and submandibular glands associated with elevated levels of serum immunoglobulin (Ig) G4 and with lymphocyte and IgG4-positive plasmacyte infiltration. It predominantly causes mouth and eye dryness but can also affect other organs such as the lungs, liver, and kidneys, and be accompanied by complications such as autoimmune pancreatitis (AIP), retroperitoneal fibrosis, and tubulointerstitial nephritis.
Mondo Term and Equivalent IDs
MONDO:0019191: IgG4-related dacryoadenitis and sialadenitis
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Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:12900
GARD:0007043
MESH:D008882
NCIT:C34819
Orphanet:79078
SCTID:7826003
UMLS:C0026103
MONDO:0019191
High level summary of knowledge for a disease, including descriptions and datasource references.