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Graves disease

Disease Summary
Associated Targets (152)
Tbio

121

Tchem

13

Tdark

11

Tclin

7


Explore Associated Targets
Mondo Description Graves' disease is an autoimmune disorder that leads to overactivity of the thyroid gland (hyperthyroidism).It is caused by an abnormal immune system response that causes the thyroid gland to produce too much thyroid hormones. Graves disease is the most common cause of hyperthyroidism andoccurs mostoften in women over age 20. However, the disorder may occur at any age and may affect males as well.Treatmentmayinclude radioiodine therapy, antithyroid drugs, and/or thyroid surgery.
Disease Ontology Description An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland.
Mondo Term and Equivalent IDs
MONDO:0005364:  Graves disease
EFO:0004237: 
GARD:0006549: 
MESH:D006111: 
NCIT:C3071: 
SCTID:353295004: 
GWAS Targets (621)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tclin
2
2
0
1.4
91.7
Tbio
2
2
0
1.4
91.7
Tdark
3
2
0
1.8
86.5
Tbio
3
2
0
1.8
86.5
Tdark
3
2
0
1.8
86.5
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tclin
0
1.4
91.7
Tbio
0
1.4
91.7
Tdark
0
1.8
86.5
Tbio
0
1.8
86.5
Tdark
0
1.8
86.5
Target Novelty (Tin-x)