You are using an outdated browser. Please upgrade your browser to improve your experience.

Exfoliation syndrome

Disease Summary
Associated Targets (7)
Tbio

5

Tchem

1

Tdark

1


Uniprot Description A disorder characterized by accumulation of abnormal fibrillar deposits in the anterior segment of the eye. In addition to being a cause of glaucoma and glaucomatous optic neuropathy, exfoliation syndrome has also been associated with lens zonule weakness, cataract formation, and systemic vascular complications due to deposition of exfoliation material in extraocular tissues.
DataSource References
DisGeNET: C0206368
CTD: DOID:13641
UniProt Disease: MIM:177650
Monarch: OMIM:177650
GWAS Targets (3)
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
4
4
0
15
99.9
Tdark
1
1
0
5.2
83.1
Tchem
1
1
0
1.2
77.8
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Tbio
0
15
99.9
Tdark
0
5.2
83.1
Tchem
0
1.2
77.8
Target Novelty (Tin-x)