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Crohn disease

Disease Summary
Associated Targets (1604)
Tbio

1127

Tchem

251

Tdark

153

Tclin

73


Explore Associated Targets
Mondo Description A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.
Disease Ontology Description An intestinal disease that involves inflammation located_in intestine.
Mondo Term and Equivalent IDs
MONDO:0005011:  Crohn disease
COHD:201606: 
DOID:8778: Crohn's disease
EFO:0000384: 
ICD9:555.1: 
NCIT:C2965: 
SCTID:7620006: 
UMLS:CN043071: 
GWAS Targets (2334)
Items per page:
1 – 5 of 2334
Target
TDL
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Uncharacterized protein C1orf141 (C1orf141)
Tdark
11
6
2
2.5
99.8
Interleukin-23 receptor (IL23R)
Tchem
11
6
2
2.5
99.8
Ubiquitin carboxyl-terminal hydrolase CYLD (CYLD)
Tbio
11
5
2
2.2
99.7
Deleted in esophageal cancer 1 (DEC1)
Tbio
9
9
0
1.7
99.6
Tumor necrosis factor ligand superfamily member 15 (TNFSF15)
Tbio
9
9
0
1.7
99.6
Items per page:
1 – 5 of 2334
Target
TDL
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
Uncharacterized protein C1orf141 (C1orf141)
Tdark
2
2.5
99.8
Interleukin-23 receptor (IL23R)
Tchem
2
2.5
99.8
Ubiquitin carboxyl-terminal hydrolase CYLD (CYLD)
Tbio
2
2.2
99.7
Deleted in esophageal cancer 1 (DEC1)
Tbio
0
1.7
99.6
Tumor necrosis factor ligand superfamily member 15 (TNFSF15)
Tbio
0
1.7
99.6
Target Novelty (Tin-x)