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ACTH-dependent Cushing syndrome
Disease Summary
Associated Targets (18)
Tbio
9
Tchem
6
Tclin
3
Mondo Description Adrenocorticotropic hormone dependent Cushing syndrome (ACTH-dependent CS) is a form of endogenous CS caused by abnormal production of ACTH due, in 80% of cases, to ACTH oversecretion by a pituitary adenoma (Cushing disease, CD) and in 20% of cases to ectopic ACTH secretion (CS due to EAS) by an extrapituitary tumor (in 50% of cases originating in the lungs or less commonly in the thymus, pancreas, adrenal gland or thyroid) or very rarely due to a tumor secreting both ACTH and corticotrophin-releasing hormone (CRH).
Counts of Target Development Levels for diseases known to be associated with this disease. If the disease has a valid DOID, targets known to be associated with all child diseases are aggregated. Click "Explore Associated Targets" to view more facets and details for the target list.
Description from Mondo Disease Ontology.
DataSources which have contributed target associations to this disease, and the identifiers by which the disease is referenced.
DOID:3946
EFO:1001110
ICD10:E24.0
MESH:D047748
Orphanet:99892
SCTID:190502001
SCTID:237734007
UMLS:C0342442
MONDO:0020528
High level summary of knowledge for a disease, including descriptions and datasource references.